Your Cart

Your cart is empty

Home  >  Volume 46 (May, 2018)

48. HIV/AIDS IN-VIVO MODEL INCORPORATING LATENCY PERIOD AND THE ROLES OF CTL IMMUNE CELLS by M. A. Ogunniran, S. Abdulrahman, B. O. Oshatuyi and T. E. Blessing Volume 46 (May, 2018 Issue), pp347 – 352
Sale price: $5.00
Quantity:

HIV/AIDS IN-VIVO MODEL INCORPORATING LATENCY PERIOD AND THE 

ROLES OF CTL IMMUNE CELLS

M. A. Ogunniran, S. Abdulrahman, B. O. Oshatuyi and T. E. Blessing

Department of Mathematics and Statistics, Niger State Polytechnic, Zungeru, Niger State, Nigeria.

Department of Mathematics, Federal University, BirninKebbi, Kebbi State, Nigeria.

Department of Mathematics, Federal University of Technology, Minna, Niger State, Nigeria. 

Department of Mathematics, Federal University, Lafia, Nasarawa State, Nigeria. 

Abstract

We proposed a mathematical model to investigate the behavior of a system infected with HIV, considering that viral particles are not produced immediately one or more CD4+T cells(s) is/are infected. Thus we introduced a latent class to account for this delay prior to when infected cells will begin the reproduction of new viral particles. With the aid of numerical simulations, we discussed the effects of the potency of drugs administered on the rate at which uninfected CD4+T cells becomes latently and actively infected and the new viral population produced by the lysing of infected cell(s).The role of Cytotoxic Lymphocyte Cells (CTL) was also discussed. 

Keywords: In-vivo, Latency, CD4+T cells, CTL Immune Cell, Reproduction Number

click here to download full Abstract
Close
Loading...